IBM To Build Next Generation Chips Using DNA
In future DNA wouldn’t just control human evolution but also computing evolution, if IBM succeeds to use DNA in development of next-generation microchips.

IBM scientists are using DNA scaffolding to build tiny circuit boards; this image shows high concentrations of triangular DNA origami binding to wide lines on a lithographically patterned surface; the inset shows individual origami structures at high resolution.
Scientists at IBM Research and the California Institute of Technology announced a scientific advancement that could be a major breakthrough in enabling the semiconductor industry to pack more power and speed into tiny computer chips, while making them more energy efficient and less expensive to manufacture.
Today, the semiconductor industry is faced with the challenges of developing lithographic technology for feature sizes smaller than 22 nm and exploring new classes of transistors that employ carbon nanotubes or silicon nanowires. IBM’s approach of using DNA molecules as scaffolding – where millions of carbon nanotubes could be deposited and self-assembled into precise patterns by sticking to the DNA molecules – may provide a way to reach sub-22 nm lithography.
The utility of this approach lies in the fact that the positioned DNA nanostructures can serve as scaffolds, or miniature circuit boards, for the precise assembly of components – such as carbon nanotubes, nanowires and nanoparticles – at dimensions significantly smaller than possible with conventional semiconductor fabrication techniques. This opens up the possibility of creating functional devices that can be integrated into larger structures, as well as enabling studies of arrays of nanostructures with known coordinates.
“The cost involved in shrinking features to improve performance is a limiting factor in keeping pace with Moore’s Law and a concern across the semiconductor industry,” said Spike Narayan, manager, Science & Technology, IBM Research – Almaden. “The combination of this directed self-assembly with today’s fabrication technology eventually could lead to substantial savings in the most expensive and challenging part of the chip-making process.”
The lithographic templates were fabricated at IBM using traditional semiconductor techniques, the same used to make the chips found in today’s computers, to etch out patterns. Either electron beam or optical lithography were used to create arrays of binding sites of the proper size and shape to match those of individual origami structures. Key to the process were the discovery of the template material and deposition conditions to afford high selectivity so that origami binds only to the patterns of “sticky patches” and nowhere else.
The paper on this work, “Placement and orientation of DNA nano structures on lithographically patterned surfaces,” by scientists at IBM Research and the California Institute of Technology, will be published in the September issue of Nature Nanotechnology and is currently available at: http://www.nature.com/nnano/journal/vaop/ncurrent/abs/nnano.2009.220.html.
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