A Neurochip That Can Communicate With Brain
August 12th, 2010 | by Anil |The University of Calgary, Faculty of Medicine scientists who proved it is possible to cultivate a network of brain cells that reconnect on a silicon chip—or the brain on a microchip—have developed new technology that monitors brain cell activity at a resolution never achieved before.
Developed with the National Research Council Canada (NRC), the new silicon chips are also simpler to use, which will help future understanding of how brain cells work under normal conditions and permit drug discoveries for a variety of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s.

Naweed Syed's lab cultivated brain cells on a microchip.
The new technology from the lab of Naweed Syed, in collaboration with the NRC, is published online this month in the journal, Biomedical Devices.
“This technical breakthrough means we can track subtle changes in brain activity at the level of ion channels and synaptic potentials, which are also the most suitable target sites for drug development in neurodegenerative diseases and neuropsychological disorders,” says Syed, professor and head of the Department of Cell Biology and Anatomy, member of the Hotchkiss Brain Institute and advisor to the Vice President Research on Biomedical Engineering Initiative of the U of C.
The new neurochips are also automated, meaning that anyone can learn to place individual brain cells on them. Previously it took years of training to learn how to record ion channel activity from brain cells, and it was only possible to monitor one or two cells simultaneously. Now, larger networks of cells can be placed on a chip and observed in minute detail, allowing the analysis of several brain cells networking and performing automatic, large-scale drug screening for various brain dysfunctions.
This new technology has the potential to help scientists in a variety of fields and on a variety of research projects. Gerald Zamponi, professor and head of the Department of Physiology and Pharmacology, and member of the Hotchkiss Brain Institute, says, “This technology can likely be scaled up such that it will become a novel tool for medium throughput drug screening, in addition to its usefulness for basic biomedical research”.


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83 Responses to “A Neurochip That Can Communicate With Brain”
By gayathri on Aug 31, 2010 | Reply
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By Zassir on Sep 7, 2010 | Reply
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By Subha on Sep 10, 2010 | Reply
In which way this Neurochip is connected with human brain?
By Sanjay Bhoye on Sep 16, 2010 | Reply
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By meena on Sep 17, 2010 | Reply
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By Rizwanmalik on Sep 24, 2010 | Reply
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By suguna on Oct 14, 2010 | Reply
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By Shashi shawal on Oct 24, 2010 | Reply
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By azie on Nov 11, 2010 | Reply
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By fff on Nov 16, 2010 | Reply
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By Ulysses on Nov 24, 2010 | Reply
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By SK.SURYA on Dec 17, 2010 | Reply
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By Vijay on Jan 7, 2011 | Reply
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By Asheley Forrester on Feb 3, 2011 | Reply
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By mulangwa on Mar 16, 2011 | Reply
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By Mena on Mar 16, 2011 | Reply
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By rahul gaba on Mar 19, 2011 | Reply
1.how will u test this neurochip with certain drugs will u make a solution of drug and dip this chip or will u spread like apowder on it and
2.Is there any device to see the changes?
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By suganya on Apr 3, 2011 | Reply
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By vamsi on Jul 28, 2011 | Reply
where will you place this chip…… if you took some cell and test …… you wont get better results i think….. can you explain some more clearly……
By SACHIN PATIL(GURJAR) on Aug 1, 2011 | Reply
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By SACHIN PATIL(GURJAR) on Aug 1, 2011 | Reply
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By Clint on Aug 30, 2011 | Reply
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By dj on Oct 13, 2011 | Reply
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