The University of Calgary, Faculty of Medicine scientists who proved it is possible to cultivate a network of brain cells that reconnect on a silicon chip—or the brain on a microchip—have developed new technology that monitors brain cell activity at a resolution never achieved before.

Developed with the National Research Council Canada (NRC), the new silicon chips are also simpler to use, which will help future understanding of how brain cells work under normal conditions and permit drug discoveries for a variety of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s.

Naweed Syed's lab cultivated brain cells on a microchip.

Naweed Syed's lab cultivated brain cells on a microchip.

The new technology from the lab of Naweed Syed, in collaboration with the NRC, is published online this month in the journal, Biomedical Devices.

“This technical breakthrough means we can track subtle changes in brain activity at the level of ion channels and synaptic potentials, which are also the most suitable target sites for drug development in neurodegenerative diseases and neuropsychological disorders,” says Syed, professor and head of the Department of Cell Biology and Anatomy, member of the Hotchkiss Brain Institute and advisor to the Vice President Research on Biomedical Engineering Initiative of the U of C.

The new neurochips are also automated, meaning that anyone can learn to place individual brain cells on them. Previously it took years of training to learn how to record ion channel activity from brain cells, and it was only possible to monitor one or two cells simultaneously. Now, larger networks of cells can be placed on a chip and observed in minute detail, allowing the analysis of several brain cells networking and performing automatic, large-scale drug screening for various brain dysfunctions.

This new technology has the potential to help scientists in a variety of fields and on a variety of research projects. Gerald Zamponi, professor and head of the Department of Physiology and Pharmacology, and member of the Hotchkiss Brain Institute, says, “This technology can likely be scaled up such that it will become a novel tool for medium throughput drug screening, in addition to its usefulness for basic biomedical research”.

 

83 Responses to A Neurochip That Can Communicate With Brain

  1. rahul gaba says:

    i do need its pdf please send it as fast as possible as i have to make a presentation on it

  2. rahul gaba says:

    please send me its pdf

  3. sathish says:

    hi sir thanks for post this actually i am doing project using brain it is very useful information to me but i need more materials will you please sent me the more materials to my mail id sathishc89@gmail.com

  4. raghu says:

    plz send me the clear information about this…

  5. Ravikant Gupta says:

    Helo sir can u plz send me the PPT Of this topic……..if possible plz send……

  6. suganya says:

    its really great and amazing……… but still could you make us clear about its working…………like will the brain be monitored continuously or whether the chip wl be placed inside the body………pls make us clear….

  7. monikka says:

    this topic is very interesting.please sent pdf to my mail

  8. ROHIT SHARMA says:

    interesting plz send me the pdf of this topic

  9. srishti arora says:

    that’s amazing

  10. [...] A Neurochip That Can Communicate With Brain [...]

  11. rinzii says:

    amazing ..wanna know the complete details..
    cud u plz mail me the pdf

  12. Aravinth N says:

    Really its very amazing. Please send its pdf format for my mail.

  13. Akash says:

    That’s a great discovery

    I want u 2 send me the PDF plz………

  14. bagyalakshmi says:

    expilain clearly how it ll useful to humambrain

  15. Prachi jadhav says:

    cool sir,

    your this invent is superb!!
    i’m engg student,
    sir,can u send me pdf??
    i want to do paper presentation on this topic on national level,if possible then send me still 3oth june.
    thaking u sir.

  16. dev says:

    podae… enna mairo….

  17. siva says:

    it’s good,but what’s gonna be in future,any way send me more info

  18. v enki says:

    it’s awesome….i wanna more details about chip ….how 2 intract the brain ..and so far

  19. vamsi says:

    where will you place this chip…… if you took some cell and test …… you wont get better results i think….. can you explain some more clearly……

  20. the concept given on the topice is mindblowing

  21. THE CONCEPT “NEUROCHIP THAT CAN COMMUNICATED
    WITH BRAIN” IS VERY INSTREATING AND I AM INTERESTED TO GET THE PDF OF THIS TOPIC PLZ SIR.

  22. gurpreet singh says:

    please sir send me detail on this topic

  23. shamna says:

    can u pls sent me the full details of neurochip used in animal brain…..i wish 2 present it…so sent me urgently…i hope u will sent thanks in advance,,,,

  24. gokila priya says:

    sir,
    it is very usefull to us but we want the detailed
    information.

  25. Ram says:

    Great..

    Can you please send me some more information to my mail?

    Thanks.

  26. Clint says:

    Could you forward me the pdf document, and if this microchip does track brain activity… How would this be a cure for alzheimers? I thought its inevitable, but this is very interesting. So please send the pdf. Keep up the good work guys.

  27. sam says:

    plz send me the pdf report and powerpoint presentations related to it.

  28. Asad says:

    send me complete detail of this ntopic

  29. arvind says:

    it is very newest topic i read today. please send me the ppt and pdf full detail of this topic. i like it.

  30. rajeswari says:

    marvellous sir plz explain it clearly

  31. kiran kumar says:

    i like this topic please send me the pdf or a ppt or details about the topic which covers all modules

  32. dj says:

    i’m interested to read more of the details in regards to this topic. hope you can send me too a pdf copy. i want to learn, how this neurochip works, and get more explanations. thank you.. i’ll appreciate your kindness.

  33. thanks for such a wonderful information.

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